Extended leadership role supports ingredient company’s strategic growth

CLEVELAND (May 17, 2016) Ganeden, one of the leading international suppliers of probiotic ingredients, has promoted Michael Bush to President of the company. Bush is well known throughout the probiotic industry for his expertise and advocacy, leading the field as both Executive Board President for the International Probiotics Association and as a sought­after speaker and media spokesperson.

Previously Ganeden’s Senior Vice President, Bush’s new role will allow him to focus on Ganeden’s strategic business development and help manage the company’s massive growth both domestically and internationally. He will also continue to oversee sales and marketing activities, while maintaining his position as a go­to expert source for media quotes, speaking engagements and educational opportunities.

“There are few people in the probiotic space more qualified than Mike Bush, and we couldn’t be more pleased to see him take on additional leadership responsibilities as Ganeden’s President,” said Andy Lefkowitz, CEO of Ganeden. “Mike’s expertise has made him an extremely valuable asset not only to Ganeden, but to the entire probiotic industry.”

Bush has been with Ganeden for over 10 years, helping to quickly and successfully build the company’s reputation as a leading probiotic ingredient manufacturer. Ganeden is best known for its patented probiotic ingredient, GanedenBC ®, which is currently used in more than 500 food, beverage and companion animal products in almost 40 countries and exceeded more than $1 billion in sales in 2015. Prior to joining Ganeden, Bush had more than 20 years of business experience and has won numerous awards for business leadership.

“The culture at Ganeden fully supports my passion for probiotics, science and innovation, and I couldn’t be more honored to take on the responsibilities of President as we innovate and delve deeper into the probiotic space,” said Bush. “I look forward to sharing Ganeden’s mission with the industry, while helping to support the probiotic industry by continuing to work with the media, CPG companies and consumers.”

For speaking opportunities or interviews with Michael, please contact Ganeden’s Public Relations Manager, Teresa DeJohn. For additional information on Ganeden and GanedenBC probiotics, visit GanedenProbiotics.com or Ganedenbc30.com.

About Ganeden:
Ganeden is at the forefront of probiotic research and product development with an extensive library of published studies and more than 100 patents for probiotic technologies in the food, beverage, animal health, sports nutrition and personal care ingredients markets. Ganeden is best known forGanedenBC ® (Bacillus coagulans GBI­30, 6086), its patented, FDA GRAS, non­GMO, highly stable probiotic ingredient. Ganeden’s newest ingredient, Bonicel, is the first science­backed, probiotic­derived, personal care ingredient shown to dramatically reduce signs of aging. For more information about Ganeden and licensing opportunities visit GanedenProbiotics.com.

About GanedenBC:
GanedenBC30® (Bacillus coagulans GBI­30, 6086), Ganeden’s patented probiotic ingredient that can be found in more than 500 leading food, beverage, sports nutrition and mpanion animal products around the world. Unlike most other probiotic strains, GanedenBC is a spore­former which makes it highly stable and allows it to remain viable through most manufacturing processes, three years of shelf life and the low pH of stomach acid. The efficacy of GanedenBC is backed by over 20 published studies showing safety, digestive and immune support and GanedenBC has an exceptional safety record with FDA GRAS status from the United States FDA. It can be formulated into virtually any food, beverage or companion animal product that is baked, boiled, frozen or squeezed….including all hot or refrigerated beverages! For more information, please visit GanedenBC30.com.

A study that found benefits in metabolic syndrome patients given Sabinsa Corporation’s Curcumin C3 Complex was chosen by a panel of experts for the NutraIngredients University Research of the Year Award, announced last week in Geneva, Switzerland. This award, given to research that “takes the nutrition sector to a new level of understanding, with clear potential for the development of market changing products,” honored the study conducted at Mashhad University of Medical Sciences on C3 Complex and metabolic syndrome.

This study investigates the safety and efficacy of Curcumin C3 Complex in management of serum lipid concentrations in metabolic syndrome patients. The study results showed that Curcumin C3 Complex plus BioPerine® combination was well tolerated and also improved the serum lipid health in metabolic syndrome patients.  (Panahi Y, Khalili N, Hosseini MS, Abbasinazari M, Sahebkar A. Lipid-modifying effects of adjunctive therapy with curcumioids-piperine combination in patients with metabolic syndrome: Results of a randomized controlled trial. Complementary Therapies in Medicine ; 2014; 22(5): 851-57).

Eight-week supplementation with Curcumin C3 Complex and BioPerine was associated with a reduction of serum triglycerides, total cholesterol, serum low density lipoprotein-cholesterol, non-high density lipoprotein cholesterol, lipoprotein (a) and increase in the high density lipoprotein cholesterol (HDL) as compared to placebo.

“Curcumin C3 Complex is the most studied Curcumin ingredient on the market, primarily for inflammation, but this study is particularly significant in that it investigates another condition that has serious health implications in a large percentage of the population,” said Sabinsa founder Dr. Muhammed Majeed. “We thank NutraIngredients and their panel of experts for acknowledging the significance of this research and we thank the researchers for carrying out this important new study.”

About Sabinsa Corporation
Sabinsa’s mission is to provide alternative and complementary natural products for human nutrition and well being. Over the past 27 years, Sabinsa has brought to market more than 100 standardized botanical extracts, and privately funded clinical studies in conjunction with prestigious institutions in support of these products. With more than 100 full-­‐time scientists conducting ongoing research in India and the United States, Sabinsa and parent company Sami Labs Ltd. continue to develop, patent and manufacture phytonutrients for the world market, with ingredients that are both Halal and osher. Branded Ingredients by Sabinsa.

We invite you to watch Prevention Magazine’s contributing editor Amy McGorry talk about things we can do to help keep our immune system strong. In addition to healthy lifestyle choices she talks about the benefits of glutathione and recommends Setria^® as the only clinically tested ingredient shown to increase levels in the blood.*

Results from new studies targeting weight loss and anti aging will be released at Vitafoods. Visit Fytexia (stand J71) to discuss opportunities with the expert team during the show.

SINETROL^®
Since Sinetrol^® proved to efficiently help with body weight management in 2 published clinical studies involving 115 subjects, the new ex-vivo study on human adipocytes reveal the synergetic benefits of polyphenols from the patented formula of Sinetrol^®: enhanced lipolytic activity and antioxidant protection.

FIIT-NS^®
Fytexia sets up a second clinical study on 92 subjects over 16 weeks on the natural ingredient Fiit-ns^®. The synergy of polyphenols and vitamin B3 targeting Quality of Life improvement.  Fiit-ns^® improves key metabolic parameters and body composition to reach a higher well-being and vitality. The supplementation impacts positively overall lifestyle by promoting healthy aging.

Bionov has launched a new website introducing SOD B EXTRAMEL^®. This website reviews all the clinical benefits of SOD B EXTRAMEL^® in improving your daily performances. http://www.extramel.com/

About Bionov
Bionov is the unique & world’s largest producer of natural and bioactive SuperOxide Dismutase (SOD) from melon. Through a green extraction process, worldwide patented, Bionov produces SOD B®: a 100% natural dried melon juice concentrate highly guaranteed in SOD. Bionov proposes SOD B® solutions backed by clinical benefits in numerous health applications:

• SOD B Extramel^® for well-being, cognitive performances, sleep quality, physical recovery and cardiac functions
• SOD B Dimpless^® for skin beauty, cellulite reduction and weight-management

Each brand is suitable for the formulation of dietary supplements and instant drinks.

Award to be Announced at VitaFoods Europe in May*

Cognizin® Citicoline is one of three finalists for NutraIngredients Ingredient of the Year at VitaFoods 2016.

Nominated in the Healthy Ageing category, Cognizin® is being considered for this prestigious honor due to its scientific merit, efficacy, innovation, and safety. The Healthy Ageing division can include everything from antioxidants, lipids, proteins, and botanicals. NutraIngredients will choose a winner that is best at “winning over formulators with an ingredient that can differentiate healthy ageing products typically aimed at ever-so-demanding Baby Boomers.”

The 2016 NutraIngredients Awards will take place on Wednesday, May 11, at the Starling Hotel in Geneva, Switzerland.

This is not the first time Cognizin® has been recognized. In 2011, the ingredient was honored by Frost & Sullivan with the Product Differentiation Excellence award in the cognitive health ingredients category. Cognizin® also won the NutrAward for best innovative ingredient at Nutracon 2004.

Cognizin® Citicoline can be found in several products available in Europe. Agave Farmaceutici produces Assonal™ with Cognizin®, a supplement meant to support conduction of nerves and protect neurons from free radicals. Bionops Laboratory offers Biomacula with Cognizin®, a daily supplement that supports eye health. FB Health offers Vivifast® with Cognizin® for optimal cognitive health.

For more information about the Cognizin® Citicoline nomination, visit NutraIngredients.com.

Citicoline is a compound that promotes the production of phosphatidylcholine (phospholipids), important for brain function. Phospholipids make up approximately 30% of brain tissue, aid neural communication and provide essential protection for neurons. Clinical research has shown that citicoline has multiple applications and is able to improve various aspects of the brain’s physiological activity.*

Cognizin® Citicoline is a branded form of citicoline, an essential substance for brain health. Citicoline works to enhance communication between neurons, maintain normal levels of acetylcholine, protect neural structures, and enhance health brain activity and energy.*

About Cognizin
Cognizin® Citicoline, manufactured by Kyowa Hakko Bio Co., Ltd., is a clinically studied and patented form of Citicoline, a natural substance found in every cell of the body and especially vital to brain health.* Citicoline is a potent brain-health nutrient. A proprietary form of citicoline, Cognizin® has been clinically studied to support mental energy, focus, attention and recall. Cognizin is manufactured through a patented fermentation process to yield high quality and high purity. Cognizin is also highly stable, GRAS, ultra-pure and allergen-free. For more information on Cognizin, visit Cognizin.com.

About Kyowa Hakko Europe
Kyowa Hakko Europe and Kyowa Hakko Bio Italia are the Central-North and South European sales office for Kyowa Hakko Bio Co., Ltd., an international health ingredients manufacturer and world leader in the development, manufacturing and marketing of pharmaceuticals, nutraceuticals and food products. For more information, visit Kyowa Hakko Europe GmbH or email bio-chemicals@kyowa.de.

New Brunswick, NJ – Natreon’s Crominex®3+ (Trivalent chromium polyphenolic complex) has been granted GRAS approval. GRAS approval demonstrates Natreon’s superiority in tests of safety regarding how it’s processed, the products constituents, and exposure to consumers.

Crominex®3+ is a unique trivalent chromium supplement prepared by complexing trivalent chromium chloride with two natural products, Phyllanthus emblica (Capros®) and purified Shilajit (PrimaVie®) in order to minimize the conversion of chromium III to toxic chromium VI. Crominex®3+ is designed to give excellent content uniformity in finished dosage forms. Two recent studies, which are currently pending publication, have shown that Crominex®3+ is much more efficacious than all the other branded chromium products (chromium picolinate, chromium polynicotinate and chromium dinicocysteinate) in reducing HbA1c levels and in improving cardiac risk factors (endothelial function, lipid profile, biomarkers of oxidative stress). In addition, it showed highly significant synergistic activity, compared to the activity of the individual components. Another published clinical study with Crominex® 3+ in adjuvant therapy with prescription oral anti-diabetic drugs in type 2 diabetics has shown that it can reduce blood glucose levels, especially post-prandial. Crominex®3+ has also been proven efficacious in pet health. Two published studies – one in arthritic dogs and the other in arthritic horses – at Murray State University in Kentucky, have shown that Crominex® 3+ has significantly reduced arthritic pain in dogs as well as horses. Crominex®3+ would be ideal as a standalone product for blood glucose support and heart health support. It can also be added to an existing heart health formula, such as a omega 3 or CoQ10, in order to have broader heart health coverage. Due to its extremely low cost (each 400 mcg dose costs ¢ 0.75), it can be added to a formula with a very minimal increase in cost. Crominex®3+ is a safe and efficacious product that does much more than JUST blood glucose support.

For more information on Crominex®3+ and Natreon’s other patented ingredients, please visit www.natreoninc.com.

About Natreon Inc.
Natreon Inc. is a 16 year old company located in New Jersey with a state of the art R&D facility in Kolkata, India, and is focused on developing and marketing Ayurvedic products backed by extensive research, high degree of standardization, multiple clinical studies, safety studies, and intellectual property. Natreon’s R&D team is headed by Prof. Shibnath Ghosal, a Fulbright scholar and an eminent natural product chemist with hundreds of publications in scientific journals and a group of Ph.D. and Master’s level scientists. Natreon’s scientific research includes process optimization, development of chromatographic analytical methods such as HPLC, HPTLC, GC-MS and LC-MS for standardization, development of marker compounds, and pharmacological studies. Safety studies are done in the USA and clinical studies are conducted in reputed institutes in India as well as the USA.
For more information on PrimaVie® and Natreon’s other patented ingredients, please visit www.natreoninc.com.

Supplement Designed to Support Memory, Focus, and Attention*

EZ Melts® Citicoline is now available with a 250mg dose of Cognizin® Citicoline.

EZ Melts® are specially formulated to melt in the mouth without the need for water – great for people who dislike swallowing pills or are unable to do so for medical or lifestyle reasons. Active ingredients, such as Cognizin®, are quickly dissolved before entering the digestive tract, which means nutrients are more readily available for absorption and able to reach the areas of the body where it’s needed most.*

“EZ Melts® Citicoline is a simple, clean formula that combines Cognizin® with our premium ingredients and fast-dissolving delivery system,” said Nina Dyatchenko, EZ Melts® formulation scientist. “This elegant formulation is an excellent fit for production and the consumer.”

EZ Melts® Citicoline comes in a Strawberry Blast flavor that is gluten-, dairy-, GMO-, and sugar-free. But the real power comes from Cognizin® Citicoline, which supports the production of vital neurotransmitters and protection of healthy brain cells.*

Citicoline is a compound that promotes the production of phosphatidylcholine (phospholipids), important for brain function. Phospholipids make up approximately 30% of brain tissue, aid neural communication and provide essential protection for neurons. Clinical research has shown that citicoline has multiple applications and is able to improve various aspects of the brain’s physiological activity.*

For more information about EZ Melts® Citicoline, visit EZ Melts.

About EZ Melts
Creating EZ Melts® is a unique blend of science and art. Our team of scientists brings over 40 years of combined experience to create product formulations in an oral-dissolving form, perfect for those who can’t handle swallowing pills or simply dislike doing so. Putting these beneficial formulas into such a form is one thing – making them taste great is another. For more information, visit EZMelts.net.

About Cognizin
Cognizin® Citicoline, manufactured by Kyowa Hakko Bio Co., Ltd., is a clinically studied and patented form of Citicoline, a natural substance found in every cell of the body and especially vital to brain health.* Citicoline is a potent brain-health nutrient. A proprietary form of citicoline, Cognizin® has been clinically studied to support mental energy, focus, attention and recall. Cognizin is manufactured through a patented fermentation process to yield high quality and high purity. Cognizin is also highly stable, GRAS, ultra-pure and allergen-free. For more information on Cognizin, visit Cognizin.com.

About Kyowa Hakko USA
Kyowa Hakko USA is the North & South American office for Kyowa Hakko Bio Co. Ltd., an international health ingredients manufacturer and world leader in the development, manufacturing and marketing of pharmaceuticals, nutraceuticals and food products. Kyowa is the maker of branded ingredients including Cognizin® Citicoline, Lumistor® L-Hydroxyproline, Pantesin® Pantethine, Setria® Glutathione, as well as Sustamine® L-Alanyl-L-Glutamine.

Pleasant taste-profile and solubility of AQUALOX broadens range of applications to chews, gummies, stick-packs, shots and more

Morristown, NJ – PLT Health Solutions, Inc. announced the introduction of a water-soluble version of the company’s best-selling 5-LOXIN® for joint health support. Called AquaLOX, the new ingredient is a potent Boswellia serrata extract documented to have a similar pharmacokinetic profile to 5-LOXIN – which has been clinically demonstrated to improve joint comfort and protect against cartilage degradation. In addition to being water-soluble, AquaLOX represents a major breakthrough with its pleasant taste profile, allowing – for the first time – the use of Boswellia serrata extract for taste-sensitive formulations such as chews, gummies, stick-packs, shots and more. The technology to manufacture this pleasant-tasting, water-soluble version of Boswellia serrata has been more than five years in development.

According to Seth Flowerman, Executive Vice President at PLT Health Solutions, the development of AquaLOX was driven by a market looking to bring the efficacy, clinical support, and brand recognition of 5-LOXIN to a broad new range of product types. “5-LOXIN is a market leading joint-health ingredient, available in well over a hundred consumer products on the market today. In a market that demands convenience and novel delivery systems, all Boswellia extracts were limited because of the challenging taste profile and lack of solubility – and the technology needed to achieve this was tricky. With AquaLOX, we are finally able to deliver on our customers’ wish list and extend the 5-LOXIN franchise to a whole new range of products,” he said.

Clinically-studied support for joint comfort and mobility

In a recent human study,5-LOXIN daily provided improvement in joint comfort and mobility within 7 days. Daily consumption provided significant benefits in WOMAC, VAS and LFI standardized testing methodologies for joint health 5-LOXIN was also shown to significantly inhibit matrix metalloproteinase (MMP-3), enzymes that break down cartilage, and connective tissues. 5-LOXIN inhibits an enzyme called 5-lipoxygenase. 5-LOX inhibitors follow a distinctly different pathway than COX-2 inhibitors, and while both are involved in the breakdown of arachidonic acid, 5-LOX inhibitors do not exhibit the potentially negative effects that have been associated with COX-2 inhibitors.  5-LOXIN is a selective, non-redox 5-LOX inhibitor, which means that its action is very targeted. Safety for 5-LOXIN is supported by historic usage, published human studies, and extensive safety and toxicity studies.

About PLT Health Solutions

Headquartered in Morristown, NJ, USA, PLT Health Solutions is a trusted discoverer, developer, and marketer of high-quality, scientifically-supported ingredients that enhance health and functionality. As a leading ingredients innovator, PLT’s global network of strategic partnerships provides unique access to impactful solutions. By delivering an unsurpassed mix of expertise, resources, and service, PLT is committed to helping both its strategic partners and valued customers grow For more information, visit: PLT Health Solutions

DESIO, Italy – The partnership between Gnosis and the US nutraceutical producer Xymogen is proving innovative!

Xymogen’s XaQuil™XR, finished oral dose product containing Gnosis’ Quatrefolic®, has been selected as a finalist of NutraIngredients Awards 2016 for the Finished Product of the Year – Medical Food category.

The NutraIngredients Awards identify and celebrate stellar achievement in the fields of ingredients and finished product innovation. Being recognized as finalists underlines the   ambitious goals that Xymogen and Gnosis set when devoping  XaQuil™ XR  with Quatrefolic® for the benefit of depressed patients with suboptimal L-methylfolate levels.

XaQuil™ XR  is an innovative, orally administered, extended release medical food, that offers the metabolically active form of folate, the (6S)-5-methyltetrahydrofolate (5-MTHF), in a new time-dependent formulation. It could be especially helpful to those people who cannot metabolize folic acid effectively.

Folate deficiency is common among depressed people, especially those who don’t respond to antidepressants: major depressive disorder (MDD) currently ranks as the fourth leading disease burden worldwide and is expected to become the second global disease burden in 2020 (Hyman 2006).  XaQuil™ XR fulfills the emergent scientific data that is compelling psychiatrists to consider augmenting traditional antidepressants with a medical food L-methylfolate.

This year, more than 120 high-quality entries have been submitted to  the judging panel and 33 stand-out products and ingredients have been chosen as finalists.

Winners of the NutraIngredients Awards will be announced on Wednesday 11^th May during the annual gala dinner ceremony in Geneva, alongside Vitafoods Exhibition, where attendees, sponsors and industry professionals can network and celebrate new and significant developments with those that have successfully demonstrated their outstanding contributions to the industry.

We are all cheering for XaQuil^™XR & Quatrefolic^®!

About XaQuil^™XR
XaQuil^™XR is an innovative medical food formulated with Quatrefolic^® where the release of the active ingredients is tightly controlled for an optimization of the blood levels of 5-MTHF and can be used as an adjunctive treatment for depression.
XaQuil^™XR may constitute an effective, safe, and well tolerated medical food strategy for patients with major depressive disorder who have a partial response or no response to SSRIs (Selective Serotonin Reuptake Inhibitors).

In XaQuil^™XR Quatrefolic^® provides folate in the already biologically active form of 5-methyltetrahydrofolate, without any kind of metabolization. 5-MTHF can reach the systemic circulation and cross the blood-brain barrier, and enter straight the brain cell, for direct utilization in the folate cycle.

Gnosis and Xymogen have been working together to develop an unique extended release formulation in tablets with specific release profile of the active ingredient useful to increase the folate levels. The XaQuil^™XR formulation allows a time dependent release of the 5-MTHF in the gastroenteric system, followed by a time-dependent release of the active in the plasma. Extended-release of 5-MTHF may be crucial in partial response or no response subjects to SSRIs because normalizes the blood folate level and maximizes efficacy of XaQuil^™XR.

XaQuil^™XR. extended-release coating technology is property of Gnosis S.p.A (International Application PCT/IB2014/065852).

About Xymogen
XYMOGEN, a family-owned, health sciences company headquartered in Orlando, Fla., has been providing high-quality dietary supplements to licensed healthcare practitioners for more than a quarter century. The nutraceutical company has introduced numerous innovations to the functional medicine community; its Medical Board of Advisors consists of clinical practitioners who represent a broad range of specialties.
XYMOGEN, a family-owned, health sciences company headquartered in Orlando, Fla., has been providing high-quality dietary supplements to licensed healthcare practitioners for more than a quarter century. The nutraceutical company has introduced numerous innovations to the functional medicine community; its Medical Board of Advisors consists of clinical practitioners who represent a broad range of specialties.